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 | Acesso ao texto completo restrito à biblioteca da Embrapa Pecuária Sudeste. Para informações adicionais entre em contato com cppse.biblioteca@embrapa.br. |
Registro Completo
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Biblioteca(s): |
Embrapa Pecuária Sudeste. |
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Data corrente: |
22/11/2011 |
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Data da última atualização: |
25/07/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
GOUVEIA, G. V.; MEIRELLES, S. L.; GROSSI, D. A.; SANTIAGO, A. C.; SONSTEGARD, T. S.; YAMAGISHI, M. E. B.; MATUKUMALLI, L. K.; COUTINHO, L. L.; ALENCAR, M. M. de; OLIVEIRA, H. N.; REGITANO, L. C. de A. |
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Afiliação: |
GISELE VENERONI-GOUVEIA, UFSCar/SÃO CARLOS, SP; SARAH LAGUNA MEIRELLES, UNESP/JABOTICABAL; DANIELE A. GROSSI, UNESP/JABOTICABAL; A. C. SANTIAGO, UFSCar/SÃO CARLOS, SP; T. S. SONSTEGARD, USDA, Agricultural Research Service, Beltsville; MICHEL EDUARDO BELEZA YAMAGISHI, CNPTIA; L. K. MATUKUMALLI, USDA, Agricultural Research Service, Beltsville; LUIZ L. COUTINHO, USP-ESALQ; MAURICIO MELLO DE ALENCAR, CPPSE; HENRIQUE NUNES OLIVEIRA, UNESP/JABOTICABAL; LUCIANA CORREIA DE ALMEIDA REGITANO, CPPSE. |
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Título: |
Whole-genome analysis for backfat thickness in a tropically adapted, composite cattle breed from Brazil. |
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Ano de publicação: |
2012 |
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Fonte/Imprenta: |
Animal Genetics, v. 43, n. 5, p. 518-524, oct. 2012. |
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DOI: |
10.1111/j.1365-2052.2011.02286.x |
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Idioma: |
Inglês |
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Conteúdo: |
Backfat thickness affects the preservation of the beef carcass after slaughter and confers organoleptic characteristics assessed by the consumer. One of the breeding goals for Canchim, a tropically adapted breed, is to comprehensively increase fat thickness. Our goals were to identify genomic regions associated with backfat in Canchim populations and validate the association of single nucleotide polymorphisms (SNPs) overlapping previously identified QTL regions known to affect fat deposition. Fifteen animals with lower and 15 animals with higher residues for backfat, according to a linear model using the SAS GLM procedure, were selected from a population of 1171 animals and genotyped using the BovineSNP50 BeadChip. Initial analysis revealed more than 100 SNPs that discriminated the tails of phenotypic distribution. One extended region of association included the centromeric region of chromosome (Chr) 14. Because this region overlapped with QTL from previous reports, we developed SNP assays to interrogate two linkage disequilibrium blocks, one in the centromeric region and another in the middle region of Chr 14 to confirm the association. The analysis validated the presence of specific haplotypes affecting fat thickness. |
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Palavras-Chave: |
Fat deposition; Tropically adapted cattle. |
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Thesaurus NAL: |
single nucleotide polymorphism. |
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Categoria do assunto: |
G Melhoramento Genético |
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Marc: |
LEADER 02153naa a2200289 a 4500
001 1906584
005 2022-07-25
008 2012 bl uuuu u00u1 u #d
024 7 $a10.1111/j.1365-2052.2011.02286.x$2DOI
100 1 $aGOUVEIA, G. V.
245 $aWhole-genome analysis for backfat thickness in a tropically adapted, composite cattle breed from Brazil.$h[electronic resource]
260 $c2012
520 $aBackfat thickness affects the preservation of the beef carcass after slaughter and confers organoleptic characteristics assessed by the consumer. One of the breeding goals for Canchim, a tropically adapted breed, is to comprehensively increase fat thickness. Our goals were to identify genomic regions associated with backfat in Canchim populations and validate the association of single nucleotide polymorphisms (SNPs) overlapping previously identified QTL regions known to affect fat deposition. Fifteen animals with lower and 15 animals with higher residues for backfat, according to a linear model using the SAS GLM procedure, were selected from a population of 1171 animals and genotyped using the BovineSNP50 BeadChip. Initial analysis revealed more than 100 SNPs that discriminated the tails of phenotypic distribution. One extended region of association included the centromeric region of chromosome (Chr) 14. Because this region overlapped with QTL from previous reports, we developed SNP assays to interrogate two linkage disequilibrium blocks, one in the centromeric region and another in the middle region of Chr 14 to confirm the association. The analysis validated the presence of specific haplotypes affecting fat thickness.
650 $asingle nucleotide polymorphism
653 $aFat deposition
653 $aTropically adapted cattle
700 1 $aMEIRELLES, S. L.
700 1 $aGROSSI, D. A.
700 1 $aSANTIAGO, A. C.
700 1 $aSONSTEGARD, T. S.
700 1 $aYAMAGISHI, M. E. B.
700 1 $aMATUKUMALLI, L. K.
700 1 $aCOUTINHO, L. L.
700 1 $aALENCAR, M. M. de
700 1 $aOLIVEIRA, H. N.
700 1 $aREGITANO, L. C. de A.
773 $tAnimal Genetics$gv. 43, n. 5, p. 518-524, oct. 2012.
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Embrapa Pecuária Sudeste (CPPSE) |
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